382 FRONTAL PLANE MALALIGNMENT AND CARTILAGE Tip AND T2 RELAXATION TIMES IN KNEE OSTEOARTHRITIS

The Effects of Different Walking Inclinations on Knee Angle in the Frontal Plane of Patients with Varus Malalignment

Purpose: Given the high prevalence of varus malalignment of the knee and the consequences of walking on different surfaces on this malalignment, the aim of the present study was to investigate the effect of walking inclination on knee angle in the frontal plane of patients with varus malalignment. Methods: 18 male subjects with varus malalignment classified at grade 3 bowleg, within the a...

Multi-component T2* relaxation of knee cartilage under UTE acquisitions

INTRODUCTION This work reports observations of T2* relaxation in human knee cartilage explants under ultrashort echo time (UTE) acquisitions in vitro. The objective of this study was to determine the number and distribution of T2* components. We hypothesize that the three major constituents of articular cartilage extracellular matrix (water, collagen, and proteoglycan) contribute to the existen...

Correlation of T1ρ and T2 Relaxation Times Values with Glycosaminoglycan and Water Content of Articular Cartilage

T1ρ/T2 mapping and histopathology of degenerative cartilage in advanced knee osteoarthritis

AIM To investigate whether normal thickness cartilage in osteoarthritic knees demonstrate depletion of proteoglycan or collagen content compared to healthy knees. METHODS Magnetic resonance (MR) images were acquired from 5 subjects scheduled for total knee arthroplasty (TKA) (mean age 70 years) and 20 young healthy control subjects without knee pain (mean age 28.9 years). MR images of T1ρ map...

Long-term and short-term reproducibility of T2 relaxation time in human knee cartilage

INTRODUCTION T2 relaxation time of articular cartilage has been reported to reflect the orientation and concentration of collagen fibrils [1-2]. The reproducibility of T2 in human patellar cartilage has been reported to be close to 5% [3]. However, the patellar cartilage is the thickest one in the knee, and the reproducibility in other articular surfaces has not been studied earlier. In this st...